I'd use 1280x720. People still have laptops that have native resolutions smaller than 1080p, but 720p should be fine for everybody.
That way the game size is roughly halved on top.
As for the GUIs, I personally dislike hand-drawn GUIs even with a hand-drawn game. I usually wouldn't mix pixel sizes but Whispers of a Machine pulls it off really great imo:
That way the game size is roughly halved on top.
As for the GUIs, I personally dislike hand-drawn GUIs even with a hand-drawn game. I usually wouldn't mix pixel sizes but Whispers of a Machine pulls it off really great imo: